Charles Perou
Professor, Lineberger Comprehensive Cancer Center

He earned his Bachelor’s degree in Biology from Bates College, his PhD in Cell Biology from the University of Utah, and performed his postdoctoral work in the laboratory of David Botstein (then at Stanford University).

Dr. Perou’s research crosses the disciplines of genomics, cancer biology, bioinformatics, epidemiology, and clinical trials. A major contribution of his has been in the characterization of the genomic diversity of breast tumors, which resulted in the discovery of the Basal-like/Triple-Negative Breast Cancer subtype. He and his colleagues demonstrated that breast cancers can be classified into at least five molecular subtypes, with his lab focusing particular attention on the Basal-like subtype. He is also elucidating the genetic causes that give rise to each subtype, modeling these events in Genetically Engineered Mouse Models, and then using these models to investigate tumor biology and the efficacy of new drugs and new drug combinations. Dr. Perou has also translated these molecular finding into human population-based studies